200000 BC/ca. 40,000 years ago to 1783 A.D. – Mission to Earth/The previous versions of Fry, Bender and Professor Farnsworth watch the Neanderthals in North America killed by Paleo-Indians (in one reality, they do not watch this). (Alternate Fisrt, Second and Third)

26987 BC – Homo sapiens drive the Neanderthals from the Neander Valley. Neanderthals settle in a nearby glacier along with several prehistoric creatures.

15000 BC – is when the Paelo-Indians lived in America (The previous versions of Fry, Bender and Professor Farnsworth watch for Alternate Second and Third)

10000 BC – Three tribes, the Wenja, Udam, and Izila settle in the region of present-day Central Europe known as Oros, sparking conflict (Tribal War in Oros) for resources and territory. (Possibly Alternate First)

23rd October 4004 BCE – The Earth and all life on it is created, according to the chronology of Archbishop James Ussher, to which creationists will cling well into the 31st century.